TruDiagnostic
Decode Your DNA For Better Aging
At-home epigenetic testing from a CLIA lab, with TruAge biological-age clocks and TruHealth nutrition/toxin panels
About
TruDiagnostic is a Lexington, Kentucky testing company focused on DNA methylation: how gene expression patterns change with age, environment, and intervention. Its CLIA-certified lab processes at-home dried-blood-spot samples for TruAge, the biological-age product built around OMICmAge, SYMPHONYAge, and DunedinPACE, and TruHealth, a nutritional, metabolic, toxin, and inflammation panel. The company also runs epigenomics and bioinformatics services for research partners, which keeps the consumer products close to its scientific publication and clinical-trial pipeline.
Reviews
What to Know
Signature approach
One at-home dried-blood-spot sample feeds TruDiagnostic's methylation workflow. TruAge reads 1M+ CpG sites for biological age, pace of aging, organ-system ages, telomere length, and immune-cell estimates; TruHealth uses methylation-derived algorithms for nutritional, metabolic, toxin, and inflammation markers. The same lab also serves research partners, so consumer reporting and scientific model development are tightly connected.
What sets them apart
- Three academic-partner clocks. TruAge bundles OMICmAge (Harvard), SYMPHONYAge (Yale), and DunedinPACE (Duke + Columbia) in one retail kit.
- Blood-spot methylation model. TruDiagnostic uses at-home dried blood spot collection instead of saliva, while keeping the collection easier than venous lab panels.
- Research engine behind the shop. A large private methylation database, 30+ clinical trials, B2B epigenomics work, and a dedicated bioinformatics team support the consumer products.
Before You Book
- Plan your interpretation. Retail kits deliver a dashboard and report; bring results to your clinician or use a TruDiagnostic provider channel if you want guided clinical review. - Choose the right kit. TruAge is for biological-age clocks; TruHealth is for nutrition, metabolic, toxin, and inflammation markers; the combo covers both. - Check retest cadence. One-time kits are best for a baseline. The $1,799/qtr/year subscription ships four kits for quarterly retesting and is US-only. - Use checkout pricing. Promotions change, so confirm the final shop price before ordering.
Services
Consumer Epigenetic Testing
6 offeringsTruAge — at-home finger-prick epigenetic kit
OMICmAge biological age (Harvard)
SYMPHONYAge 11 organ-system ages (Yale, exclusive)
DunedinPACE pace of aging (Duke + Columbia, exclusively licensed)
Telomere length
12-cell immune deconvolution
Consumer Comprehensive Biomarker Testing
6 offeringsTruHealth — 105+ nutrient, metabolic, lipid, neurocognitive, and toxin biomarkers
Vitamin and amino-acid panels
Omega-3 / 6 fatty-acid balance
ApoB and LDL particle size
HbA1c, CRP, IL-6
Environmental toxins (PFAS, heavy metals, lead)
Bundle Kit
1 offeringTruAge + TruHealth Combo — 180+ biomarkers in a single order
B2B Research & Lab Services
4 offeringsEpigenomics — Infinium MSA, Infinium MethylationEPIC v2.0, custom arrays
Whole Genome Bisulfite Sequencing
Bioinformatics analysis and manuscript support
Genomics — gDNA analysis and Illumina GSA v4 high-density genotyping
Methylation Risk Scores Platform (B2B)
1 offeringMethylation Risk Scores (MRS) — population-scale biomarker translation platform for clinical and research partners
Interventional Trials Program
1 offeringMethylation-based clinical trials evaluating intervention impact on biological age and pace of aging
Service tags
Pricing
Starting at
$499
$499 one-time for TruAge or TruHealth; $849 for the combined TruAge + TruHealth bundle
Typical annual investment
$499/yr - $1,799/yr
Membership range estimate before any optional add-ons.
What this range includesMembership tiers, testing cadence, and common add-on examples.
A single kit is $499/yr the combo is $849/yr and a four-kit annual subscription for TruAge or TruHealth is $1,799 in the US.
In practiceAdd-ons, payment details, and coverage limits.
TruDiagnostic is self-pay; insurance is not accepted, and HSA/FSA is eligible across kits. The simple entry point is $499 for either TruAge or TruHealth. The combined kit is $849 saving about $149/qtr compared with buying both separately. Quarterly retesting runs through a $1,799/qtr/year four-kit subscription for TruAge or TruHealth, which is US-only and works out to about $450 per kit. Affirm financing is available on $499/mo kits at about $45/mo. Practitioner-led interpretation is separate from the retail kit.
TruAge
$$$$499
OMICmAge (Harvard) biological age, SYMPHONYAge (Yale) across 11 organ systems, DunedinPACE (Duke + Columbia) pace of aging, telomere length, 12-cell immune deconvolution, and 75+ longevity biomarkers — at-home finger prick, results in 2–4 weeks.
Who it’s for
First-time epigenetic testers tracking biological age and aging-pace baselines.
TruHealth
$$$$499
105+ biomarkers spanning vitamins, 20 amino acids, omega-3/6 balance, lipid particle data (ApoB, LDL size), HbA1c, neurocognitive proteins, NAD+, CRP, IL-6, and environmental toxins (PFAS, lead) from a finger-prick sample.
Who it’s for
Anyone optimizing nutritional status, metabolic health, or toxin exposure.
TruAge + TruHealth Combo
$$$$$849
Both kits — 180+ biomarkers covering biological age, organ-system aging, pace of aging, nutrients, toxins, lipids, and cognitive risk in a single ordering and reporting flow.
Who it’s for
Comprehensive baseline tester wanting both aging-clock and systems-health data.
Insurance: Self Pay · HSA/FSA: Eligible
HSA/FSA accepted on all test kits. Insurance is not accepted. Installments are available at checkout on $499 kits.
Frequently asked questions
What is epigenetics?
Epigenetics refers to changes in gene activity that do not alter the DNA sequence but can affect gene expression. These changes are influenced by factors such as lifestyle, environment, and age — they let you see how external factors impact your genetic code and overall health.
How accurate are the test results?
TruDiagnostic's tests are developed in collaboration with academic institutions and measure hundreds of thousands of CpG sites on your DNA. The published clocks (OMICmAge, SYMPHONYAge, DunedinPACE) report intraclass correlation coefficients above 0.98.
Do I need to stop medications or supplements before testing?
No — you can test on your current medications and supplements. In some cases you may want to discuss stopping supplements or medications with your physician prior to testing.
Does insurance cover this test?
No. The test is not covered by insurance. HSA and FSA funds are eligible on all kits, and Affirm financing is offered at checkout.
How does TruHealth differ from TruAge?
TruHealth measures nutritional, metabolic, immune, and cognitive biomarkers (105+) — the systems supporting longevity goals. TruAge measures biological age, pace of aging, and organ-system aging via epigenetic clocks (75+ markers, 17 age outputs). Together, the Combo bundle covers 180+ biomarkers.
Are TruDiagnostic tests CLIA certified?
Yes. TruDiagnostic's laboratory services are CLIA certified and HIPAA compliant.
Team
Hannah Went
TruDiagnostic co-founder and Everything Epigenetics host translating methylation science for clinicians and consumers
TruDiagnostic
Ryan Smith
Biochemist-operator leading TruDiagnostic's R&D, methylation algorithms, trials, and research partnerships
TruDiagnostic
Varun Dwaraka, PhD
Founding TruDiagnostic bioinformatician leading methylation pipelines, biological-age models, and peer-reviewed studies
TruDiagnostic
Matthew Dawson, MD
Emergency-medicine physician and Wild Health co-founder now leading TruDiagnostic's epigenetic testing lab
TruDiagnostic
Mike Mallin, MD
Board-certified ER physician and Wild Health co-founder shaping TruDiagnostic's epigenetic product experience
TruDiagnostic
Diagnostics
TruAge
$$$At-home epigenetic kit for biological age, pace of aging, organ-system ages, telomeres, and immune-cell estimates
TruDiagnostic
TruAge + TruHealth Combo Kit
$$$Combined TruAge and TruHealth kit with biological-age clocks plus nutrition, toxin, inflammation, and metabolic markers
TruDiagnostic
TruHealth
$$$At-home TruDiagnostic panel for nutrition, amino acids, lipids, inflammation, toxins, NAD+, and metabolic markers
TruDiagnostic
Details
Accreditations
2CLIA
TruDiagnostic operates a CLIA-certified clinical laboratory (Lexington, KY), the regulatory standard for US clinical testing labs.
HIPAA
TruDiagnostic states HIPAA compliance for handling of customer health data.
Medical advisory board
10Helen Messier, MD, PhD
Chief Medical & Science Officer, Fountain Life
Sanjeev Goel, MD, FCFP (PC), CAFCI
Lead Physician, Kennedy Medical Centre; CEO, Peak Human
Vincent C. Giampapa, MD, FACS
Founder, Regenerative Medicine Institute (Costa Rica)
Edwin Lee, MD, FACE
Founder, Institute for Hormonal Balance (Orlando)
Pamela W. Smith, MD, MPH, MS
Senior Partner, The Center For Precision Medicine
Darshan Shah, MD
Founder, Next Health
Marcos de Andrade, MD, MBA
Founder, Biohax
Jeffrey Gladden, MD, FACC
Founder, Gladden Longevity
Paul Savage, MD, FACEP, FAARM
Founder/CEO, MDLifespan
Joseph Raffaele, MD
Co-founder, PhysioAge Medical Group; Founder, Raffaele Medical Group
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