About
Eran Segal, PhD is Professor of Computational Biology at the Weizmann Institute of Science in Israel and a member of InsideTracker's Scientific Advisory Board. Trained in computer science at Tel Aviv University and a PhD from Stanford under Daphne Koller, he has been on the Weizmann faculty since 2005, building quantitative models of gene regulation, microbiome biology, and personalized medicine. His 2015 Cell paper with colleagues — showing that glucose responses to identical foods vary substantially between people — became the foundational study for biomarker- and microbiome-driven nutrition and led him to co-found DayTwo with Dr. Eran Elinav. Since 2018 he has run the Human Phenotype Project, a 25-year cohort study with 28,000+ participants as of 2025.
What to Know
Signature approach
Segal's research stack reads as the intellectual antecedent to consumer biomarker analytics platforms. Build deep multi-modal datasets — blood, microbiome, continuous glucose, imaging, lifestyle — and apply quantitative models to surface individual variation that population-average advice misses. The Personalized Nutrition Project showed glucose responses to identical foods diverge widely person-to-person; the ongoing Human Phenotype Project scales the same logic across 17 body systems and 28,000+ participants on a 25-year horizon.
What sets them apart
- Foundational personalized-nutrition paper. The 2015 Cell study (Zeevi, Korem, Zmora, Segal et al.) is the most-cited paper proving food-response heterogeneity — the empirical premise behind the personalized-nutrition category.
- Citation weight that's unusual for an advisory board. 88,000+ citations, h-index 118 on Google Scholar, Overton Prize (2007), EMBO Member (2015), three ERC grants, and a peer-reviewed publication record spanning Cell, Nature, Nature Medicine, Nature Genetics, and Nature Reviews Genetics.
- Operates the cohort, not just the lab. The Human Phenotype Project is an active 25-year longitudinal study he founded — most longevity advisors cite research; Segal generates it.
Affiliations
Scientific Advisor
Thought Leadership
Publications
- Personalized Nutrition by Prediction of Glycemic Responses · Cell, 2015
- A genomic code for nucleosome positioning · Nature, 2006
- The DNA-encoded nucleosome organization of a eukaryotic genome · Nature, 2009
- Deep phenotyping of health–disease continuum in the Human Phenotype Project · Nature Medicine, 2025
- COVID-19 dynamics after a national immunization program · Nature Medicine, 2021
Media Appearances
- Scientists Say They've Found a Code Beyond Genetics in DNA · The New York Times · 2006-07-25
- A Personalized Diet, Better Suited to You · The New York Times · 2016-01-11
- An AI model from Weizmann Institute can predict your future health · The Jerusalem Post · 2025-08-10
- Can AI-powered digital twins revolutionize healthcare? · Fast Company Middle East · 2025-09-08
Notable Collaborators
- Daphne Koller · PhD doctoral advisor, Stanford University — probabilistic models for genomic data
- Eran Elinav · Weizmann Institute immunologist; co-founder of DayTwo and lead collaborator on the Personalized Nutrition Project
- Jonathan Widom · Northwestern University; co-author on the 2006 Nature paper modeling nucleosome positioning along DNA
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