About
Adiv Johnson, PhD is Chief Science Officer at Tally Health — the in-house scientific lead behind the CheekAge buccal DNA-methylation clock that powers the company's TallyAge Test. He completed both his BS in Molecular and Cellular Biology and his PhD in Physiological Sciences at the University of Arizona (2014), then a postdoctoral fellowship in the Ophthalmology Department at Mayo Clinic (2014–2015) — early first-author work centered on bestrophinopathies and the BEST1 anion channel. After seven years at Nikon Instruments in advanced biosystems, he joined Tally in January 2022 to build out its scientific publication program. Google Scholar lists 40+ papers, h-index 27, and 3,281 citations across aging-clock, lipid-metabolism, and DNA-methylation work in Aging Cell, Ageing Research Reviews, GeroScience, and Frontiers in Aging.
What to Know
Signature approach
Johnson's research lens centers on DNA methylation as the primary readout for biological age — the science behind the CheekAge buccal clock and Tally's consumer-facing TallyAge Test. Methodologically, he leans next-generation epigenetic clocks trained on large cohorts (the published CheekAge model uses 8,000+ adults, 200,000+ methylation sites) and frames clocks as one signal among many, having co-authored the 2024 Aging Cell treatise arguing that biological age and epigenetic clocks should be conceptually detangled.
What sets them apart
- Lead scientist on a published, peer-reviewed clock. The CheekAge / TallyAge program has produced 6+ Tally-affiliated papers in GeroScience, Aging Cell, Frontiers in Aging, iScience, and Ageing Research Reviews — most consumer epigenetic-age tests cite a clock; Johnson's group built one and published the validation arc.
- 17-year aging-research arc, h-index 27. Active in the field since 2008, with 3,281 Google Scholar citations and 40+ peer-reviewed papers spanning DNA methylation, lipid metabolism, proteomic clocks, and bestrophinopathies — broader than most consumer-test scientific leads.
- Cross-disciplinary provenance. Mayo Clinic ophthalmology postdoc (bestrophin / retinal disease) before pivoting fully into aging biology — an unusual lineage among epigenetic-clock leads who typically come from biostatistics or developmental biology.
Affiliations
Head of Research
Thought Leadership
Publications
- The role of DNA methylation in aging, rejuvenation, and age-related disease · Rejuvenation Research, 2012
- The role of lipid metabolism in aging, lifespan regulation, and age-related disease · Aging Cell, 2019
- Bestrophin 1 and retinal disease · Progress in Retinal and Eye Research, 2017
- Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age · Ageing Research Reviews, 2020
- Human age reversal: Fact or fiction? · Aging Cell, 2022
- Glycine and aging: Evidence and mechanisms · Ageing Research Reviews, 2023
- Apigenin: a natural molecule at the intersection of sleep and aging · Frontiers in Nutrition, 2024
- Revamping the evolutionary theories of aging · Ageing Research Reviews, 2019
- A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes · iScience, 2022
- CheekAge: a next-generation buccal epigenetic aging clock associated with lifestyle and health · GeroScience, 2024
- CheekAge, a next-generation epigenetic buccal clock, is predictive of mortality in human blood · Frontiers in Aging, 2024
- Various diseases and conditions are strongly associated with the next-generation epigenetic aging clock CheekAge · GeroScience, 2025
Media Appearances
- New study shows CheekAge clock is 'significantly associated' with health and disease variables (quoted as Tally Health head of scientific affairs) · Longevity.Technology · 2025-03-07
- RAADfest speaker — Dr. Adiv Johnson · RAADfest
- A4M faculty appointment · American Academy of Anti-Aging Medicine
Notable Collaborators
- Maxim N. Shokhirev, PhD · Tally Health Head of Computational Biology and Data Science — co-author on proteomic aging clock and aging transcriptome papers
- David A. Sinclair, PhD · Tally Health cofounder — co-author on 'Human age reversal: Fact or fiction?' (Aging Cell, 2022)
- Trinna L. Cuellar, PhD · Former Tally scientist, current Tally SAB — co-author on 'Human age reversal' and 'Glycine and aging' reviews
- Tony Wyss-Coray, PhD · Stanford — co-author on the 2020 proteomic aging clock paper in Ageing Research Reviews
- Benoit Lehallier, PhD · Stanford / Alkahest — co-author on plasma-proteomics aging clock work
Other specialists at Tally Health
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