Original Manhattan home of Dr. Florence Comite's N-of-1 precision-medicine practice on Central Park South
Walk-ins: Appointment Only
Amenities & highlights
The New York center is the original Comite practice, opened in 2005 by Florence Comite, MD, and remains the home base for the three-location network. The office occupies the second floor of Hampshire House, a 1937 Art Deco landmark on Central Park South between 6th and 7th Avenues. This is where Dr. Comite built the N-of-1™ method that later extended to the Bay Area and Miami Beach, and it is the location most closely tied to her public teaching, media appearances, and day-to-day clinical leadership.
Care here pairs the full N-of-1™ program with the practice's deepest founder presence. Patients come into the original center for longitudinal biomarker review, wearable-data interpretation, and personalized intervention planning, with Dr. Comite's endocrinology and healthy-aging framework shaping the clinical model that the satellite centers follow.
Location map
Pricing is handled through inquiry rather than a public tier menu. Treat Comite as a high-touch concierge longitudinal program, not a one-time executive physical: the cost conversation should cover annual access, repeat biomarker panels, clinician follow-up, and any medications, supplements, imaging, or specialty work billed separately. Medicare opted-out status is listed for Dr. Comite on IDNY, so plan around self-pay concierge economics. Ask which diagnostic line items can be submitted through HSA/FSA or insurance paperwork.
Insurance: Self Pay · HSA/FSA: Partial
Treat membership or concierge-program fees as unlikely to qualify. Select lab, imaging, or diagnostic line items may be eligible depending on plan rules, so confirm with Comite and your plan administrator.
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