Masaki Nakao, PhD
Director · Tokyo Relife Clinic
Stem cell, exosome, fibroblast, and anti-aging care from an ophthalmologist with Harvard retinal-cell research training
About
Masaki Nakao, PhD brings an ophthalmology and cell-biology background to Tokyo Relife Clinic's regenerative medicine program. She trained at St. Marianna University School of Medicine, completed graduate work in regenerative medicine and immunopathology, and later joined Massachusetts Eye and Ear Infirmary at Harvard Medical School as a research fellow. Her published work under the name Kayama M focuses on retinal cell stress, photoreceptor death, and corneal regeneration. Appointed Director in 2026, she now leads the clinic's stem cell, exosome, fibroblast, and anti-aging care in Ginza.
What to Know
Signature approach
Nakao's clinical lens starts with diagnostic detail and individualized planning. Her ophthalmology background shows in the emphasis on small functional changes that affect quality of life, while her regenerative-medicine training supports Tokyo Relife's use of stem cell, exosome, and fibroblast protocols. Expect a physician-led plan built around biomarkers, goals, treatment eligibility, and careful communication.
What sets them apart
- Retinal-cell research at Harvard. Nakao spent her post-PhD research period at Massachusetts Eye and Ear Infirmary, Harvard Medical School, working in the biology of retinal injury and regeneration.
- Published cell-biology work. Her confirmed papers under Kayama M cover photoreceptor stress response, TNF-alpha-mediated cell death, and embryonic stem cell-derived corneal epithelial cells.
- Ophthalmology plus anti-aging medicine. She carries Japanese board certification in ophthalmology and anti-aging medicine, giving Tokyo Relife a clinical director with both specialty-care and regenerative-science grounding.
Before You Book
- Confirm the physician assignment. Nakao is listed as Director; for a high-spend regenerative protocol, ask whether she personally handles your consult, procedure planning, infusion review, or follow-up.
- Plan around cell-therapy timing. Stem cell care can require separate visits for consultation, tissue collection, culture, and infusion. Ask for the schedule before booking travel.
- Use the clinic's language support. Nakao's core language is Japanese; the clinic also lists English and Simplified Chinese support for international patients.
Expertise
Focus areas
Patient types
Protocols & technologies
Credentials
Education
MD
St. Marianna University School of Medicine (1997)
Graduate Studies, Regenerative Medicine and Immunopathology
St. Marianna University (2005)
PhD, Medicine
St. Marianna University (2009)
Board certifications
Board-Certified Ophthalmologist
Japanese Ophthalmological Society
Certified specialist in eye care and surgery by Japan's primary ophthalmology society
Board-Certified Specialist
Japanese Society of Anti-Aging Medicine
Certified in anti-aging medicine by Japan's leading anti-aging medical society
Fellowship
Ophthalmology / Regenerative Medicine
Massachusetts Eye and Ear Infirmary, Harvard Medical School
Additional certifications
Certified Physician, Juvederm Vista
Allergan
Certified to perform hyaluronic acid filler injections
Certified Physician, Botox Vista
Allergan
Certified to perform botulinum toxin injections
Years in practice
29
Affiliations
Thought Leadership
Publications
- Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase · American Journal of Pathology, 2011
- Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment · Investigative Ophthalmology & Visual Science, 2011
- Recent advances in corneal regeneration and possible application of embryonic stem cell-derived corneal epithelial cells · Clinical Ophthalmology, 2009
Other specialists at Tokyo Relife Clinic
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