Constantine Stratakis, MD, D(Med)Sci, PhD
Co-founder and Director, Astrea Health · Astrea Health
Medical genetics and endocrine-genetics care from a former NIH/NICHD director
About
Constantine A. Stratakis, MD, D(Med)Sci, PhD is Astrea Health's co-founder and director. He trained in medicine in Athens, then completed pediatrics, endocrinology, and medical genetics at Georgetown University before a long NIH/NICHD career leading genetics and endocrinology programs. His research record includes 800+ publications, 62,000+ Google Scholar citations, the identification of PRKAR1A in Carney complex, and the disease eponym Carney-Stratakis syndrome. At Astrea, that background anchors the clinic's clinical-genetics and longevity-planning model.
What to Know
Signature approach
Stratakis reads genomic findings through a physician's endocrine and tumor-genetics lens. Whole-exome or targeted-panel results are interpreted against family history, hormone-axis questions, and disease-risk patterns, then translated into prevention, surveillance, counseling, or treatment decisions. The consult is genetics-forward, with longevity planning built from risk signals rather than broad wellness advice.
What sets them apart
- Rare research depth in a clinic director. 800+ publications, h-index 124, and 62,000+ Google Scholar citations give his Astrea role a substantial genetics-research base.
- NIH operating scale. He directed NIH/NICHD intramural research programs with roughly 1,100 staff and a $200M annual budget.
- Named endocrine-genetics contribution. Carney-Stratakis syndrome bears his name, and his work helped define the genetics of Carney complex.
Before You Book
- Ask for fit. He is best used for complex genetics, endocrine-genetics, hereditary-risk, or precision-medicine questions where his depth changes the interpretation.
- Coordinate availability. He also holds academic and research roles at IMBB/FORTH and the University of Athens, so direct appointment timing should be confirmed early.
- Team-based workflow. Counseling, sampling, and follow-up may involve Astrea's broader genetics and lab team even when his clinical oversight shapes the case.
Expertise
Focus areas
Patient types
Credentials
Education
MD, Medicine
University of Athens, School of Medicine (1989)
D(Med)Sci, Medical Sciences
University of Athens
Honorary PhD
University of Liege
Honorary PhD
University of Athens
Executive Leadership Program
University of Maryland School of Public Policy
Residency
Pediatrics
Georgetown University, Washington DC
Fellowship
Endocrinology and Medical Genetics
Georgetown University, Washington DC
Affiliations
Thought Leadership
Books
- Gigantism and Acromegaly · Elsevier
Publications
- Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation · New England Journal of Medicine, 2014
- Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations · Proceedings of the National Academy of Sciences, 2011
- A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia · Nature Genetics, 2006
- A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues · Cancer Research, 2005
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