Elysium Health
Translating critical scientific advancements in aging research into accessible health products and technologies.
At-home Index epigenetic biological-age testing from an MIT-rooted consumer health company
About
Elysium Health is a New York consumer health company founded in 2014 by Eric Marcotulli, Dan Alminana, and MIT aging biologist Leonard Guarente, PhD. Its testing product is Index, a $299 at-home saliva DNA-methylation test that returns biological age, cumulative pace of aging, and nine system-age scores. Index runs on a custom methylation chip developed with Illumina and Elysium's proprietary APEX algorithm, with methodology published in Nature Aging through work with Yale epigeneticist Morgan Levine, PhD. Elysium also sells supplements such as Basis, which help explain the company but are separate from the Index testing experience.
What to Know
Signature approach
Elysium's directory role is testing, not clinical care. Index translates academic methylation-clock work into a consumer saliva kit: custom Illumina chip, APEX algorithm, Yale-linked methodology, and optional TIME-A longitudinal research participation. That sits alongside Elysium's supplement business, with Guarente's MIT sirtuin/NAD+ background giving the company its original aging-biology foundation.
What sets them apart
- Peer-reviewed Index methodology. The APEX methylation-clock approach was published in Nature Aging through work with Morgan Levine, PhD.
- MIT aging-biology roots. Co-founder Leonard Guarente, PhD is a major sirtuin/NAD+ researcher and directs MIT's Glenn Center for the Biology of Aging.
- TIME-A research loop. Index users can opt into Elysium's longitudinal Aging Research Center study.
- Deep advisory board. Nobel laureates and senior faculty give Elysium a larger academic bench than most DTC biological-age brands.
Before You Book
- Index is the testing product. Supplements like Basis and Matter are relevant context, but the buyer flow here is biological-age testing.
- Plan for portal-based results. Index gives a report and lifestyle recommendations, with no clinician review built in.
- Budget for self-pay. Insurance is not accepted, and HSA/FSA approval depends on the user's card provider.
- Expect a longer turnaround. Results take about six weeks from lab receipt, which is normal for methylation testing but slower than many standard lab panels.
Services
At-home epigenetic biological age testing
4 offeringsIndex — saliva DNA methylation test
Biological age + cumulative pace of aging
9 system age scores (brain, heart, metabolic, immune, inflammation, kidney, liver, hormone, blood)
TIME-A longitudinal study enrollment (optional, free)
Service tags
Pricing
Starting at
$299
$299 one-time for the Index biological age test kit.
Typical annual investment
$299/yr - $299/yr
Membership range estimate before any optional add-ons.
What this range includesMembership tiers, testing cadence, and common add-on examples.
Index is a one-time $299/yr kit, not an annual subscription. Most users re-test once a year or less to track changes — a single kit is the typical annual spend.
In practiceAdd-ons, payment details, and coverage limits.
Index is a $299 one-time kit that includes saliva collection, lab processing, and the digital report. There is no actively merchandised subscription tier, clinician review, or add-on consultation. Traditional insurance is not accepted. HSA/FSA cards are case-by-case because Elysium does not pre-approve them or advertise a Truemed-style flow. Refunds are limited to unopened, unused kits within the Terms of Service window.
Insurance: Self Pay · HSA/FSA: Partial
Elysium does not pre-approve HSA/FSA cards and the Index product page does not advertise HSA/FSA eligibility. Per Elysium's payment FAQ, card approval depends on the user's HSA/FSA bank.
Frequently asked questions
What does Elysium Health sell that's in this directory?
Index is the modeled product: a $299 at-home saliva DNA-methylation test that returns biological age, cumulative pace of aging, and biological ages for nine body systems. Elysium's supplement line is company context, not separate directory products.
How is Index different from other consumer biological age tests?
Index uses a custom methylation chip developed with Illumina and Elysium's APEX algorithm, built with academic input from Morgan Levine, PhD at Yale. The methodology was published in Nature Aging in 2022.
Does Index include a clinician consultation?
No. The report is delivered through the Elysium customer portal with more than 100 evidence-based lifestyle recommendations. Elysium does not bundle physician review or sell it as an add-on.
How long do results take?
Approximately six weeks from lab receipt. DNA extraction, methylation profiling, APEX analysis, quality control, and report generation all happen before results land in the customer portal.
Is the test covered by insurance?
Traditional insurance is not accepted. HSA/FSA card use is case-by-case because Elysium does not pre-approve those cards or advertise Index as HSA/FSA eligible.
Can I get a refund?
Refunds are limited to unopened, unused kits when Elysium is notified within the Terms of Service window. Opened or used kits are treated as final sale.
Where is Elysium Health based?
Elysium is based in New York and operates as a direct-to-consumer online business. There is no patient-facing clinic location.
Who is on the Scientific Advisory Board?
Elysium's Scientific Advisory Board includes Nobel laureates and senior faculty across aging biology, genetics, nutrition, neuroscience, and clinical medicine, with names from institutions including MIT, Yale, Stanford, Oxford, Mayo Clinic, Columbia, Tufts, Rutgers, Harvard, and UC San Diego.
Team
Ryan Dellinger, PhD
Elysium VP of Scientific Affairs leading product science, collaborations, and TIME-A study work
Elysium Health
Dan Alminana
Elysium Health co-founder and COO bringing finance and operating experience to the Index testing company
Elysium Health
Dayle Sampson, PhD
Elysium VP of Bioinformatics leading APEX algorithm work behind the Index biological-age test
Elysium Health
Leonard Guarente, PhD
MIT aging biologist and Elysium Chief Scientist known for foundational sirtuin and NAD+ research
Elysium Health
Eric Marcotulli
Elysium Health co-founder and CEO bringing venture and consumer-health operating context to Index
Elysium Health
Diagnostics
Details
Medical advisory board
29Carolyn Bertozzi, PhD, Nobel Prize in Chemistry (2022)
Bioorthogonal Chemistry and Glycoscience, Stanford University
Aaron Ciechanover, MD, DSc, Nobel Prize in Chemistry (2004)
Cancer Biology, Technion — Israel Institute of Technology
Eric Kandel, MD, Nobel Prize in Physiology or Medicine (2000)
Neuroscience, Columbia University
Martin Karplus, PhD, Nobel Prize in Chemistry (2013)
Complex Chemical Systems, Harvard University
Paul Modrich, PhD, Nobel Prize in Chemistry (2015)
Biochemistry, Duke University School of Medicine
Sir Richard Roberts, PhD, Nobel Prize in Physiology or Medicine (1993)
Biochemistry, New England Biolabs
Thomas Südhof, MD, Nobel Prize in Physiology or Medicine (2013)
Neuroscience, Stanford University
Sir Jack Szostak, PhD, Nobel Prize in Physiology or Medicine (2009)
Origins of Life and Telomeres, University of Chicago
Martin J. Blaser, MD, Microbiology
Rutgers University
Ana Maria Cuervo, MD, PhD, Aging & Neuroscience
Albert Einstein College of Medicine
Russell Foster, PhD, Circadian Neuroscience
University of Oxford
Michael Fredericson, MD, Sports Medicine
Stanford University
Mark B. Gerstein, PhD, Genomics & Bioinformatics
Yale University
Richard Granstein, MD, Dermatology
Weill Cornell Medicine
Stephen Kennedy, MD, Reproductive Medicine
University of Oxford
Stuart Kim, PhD, Genetics
Stanford University School of Medicine
Ross D. King, PhD, Machine Learning and Optimisation
The University of Manchester
Jim Kirkland, MD, PhD, Aging
Mayo Clinic
Theodore Leng, MD, Ophthalmology
Stanford University School of Medicine
Bruce McEwen, PhD, Neuroendocrinology
The Rockefeller University
David Moore, PhD, Nutritional Sciences and Toxicology
University of California, Berkeley
Dariush Mozaffarian, MD, DrPH, Cardiometabolic Health
Tufts University
Bijan Salehizadeh, MD, Healthcare
NaviMed Capital
Mark Sarzynski, PhD, Exercise Science
University of South Carolina
Eric Schadt, PhD, Precision Medicine
Icahn School of Medicine at Mount Sinai
A. David Smith, FMedSci, Pharmacology
University of Oxford
Meir Stampfer, MD, DrPH, Epidemiology and Nutrition
Harvard T.H. Chan School of Public Health
Yousin Suh, PhD, Reproductive Sciences, Genetics, & Development
Columbia University
Ajit Varki, MD, Cellular & Molecular Medicine
UC San Diego School of Medicine
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