Caleb Calkins, MD

Family-medicine physician focused on hormones, metabolism, nutrition, fitness, GLP-1s, and root-cause wellness

Hormone OptimizationMetabolic HealthFunctional MedicineEnglish
Caleb Calkins, MD portrait

About

Caleb Calkins, MD, is a Defy Medical physician with family-medicine training and a metabolism-forward clinical lens. He studied public relations with a nutritional science minor at the University of Florida, joined ketogenic-diet research as an undergraduate, earned his MD from St. Matthew's University, and completed family-medicine residency at Tulane University / East Jefferson General Hospital. He also holds a master's in hospital administration from Davenport University. At Defy, his work sits at the intersection of hormones, metabolism, nutrition, fitness, GLP-1 weight care, and broader wellness optimization.

What to Know

Signature approach

Calkins approaches hormone and weight-care visits as a connected system. Labs, symptoms, diet, training, thyroid markers, metabolic health, and recovery all shape the plan. Depending on the findings, care may involve TRT, BHRT, menopause support, GLP-1 weight management, peptides, lifestyle protocols, or follow-up testing. The hospital-administration training adds a practical systems lens to the way he thinks about care delivery.

What sets them apart

  • Family medicine plus hospital administration. The MHA adds a care-systems perspective to his clinical work.
  • Metabolism-forward background. His early nutrition and ketogenic-diet research aligns with Defy's hormone, metabolic, GLP-1, and peptide menu.
  • Physician role on a team of mixed credentials. As an MD on the Defy roster, he is one of the physician options alongside the broader PA and NP team.

Before You Book

  • Confirm provider assignment. Defy uses a team model, so ask during intake if you specifically want Calkins.
  • Use the company pricing envelope. Hormone, GLP-1, peptide, lab, and medication costs are priced through Defy's self-pay model.
  • Plan for labs first. Defy requires lab work and a recent physical exam before hormone prescribing.
  • Check telehealth rules. State coverage, lab access, and prescribing requirements can affect the care path.

Expertise

Focus areas

Hormone OptimizationMetabolic HealthFunctional Medicine

Patient types

Men 40+Women in Perimenopause & MenopauseMetabolic & Weight ManagementGeneral Adult Longevity

Credentials

Education

  • MD

    St. Matthew's University (2012)

  • MHA, Hospital Administration

    Davenport University

  • BS, Public Relations (minor: Nutritional Science)

    University of Florida

Residency

  • Family Medicine

    Tulane University / East Jefferson General Hospital (New Orleans, LA)

NPI

1700229739

Affiliations

Staff Physician

Tampa, FL

Other specialists at Defy Medical

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