Rapamycin Bioavailability Panel
Targeted sirolimus blood-level testing for rapamycin absorption, clearance, and dose-timing decisions
Single-analyte sirolimus test for rapamycin users choosing peak, trough, or mid-cycle timing for dose insight
Biomarkers
1 analyte (sirolimus blood serum)
Collection
In-lab
Turnaround
Typically 2-3 weeks after lab draw
Price
$25
Physician reviewed
Yes
Membership
Not required
About
Rapamycin Bioavailability Panel is a single-analyte sirolimus blood serum test for users already taking rapamycin and trying to understand absorption, clearance, or dose timing. The patient chooses the draw window: peak around 3-4 hours post-dose, trough before the next dose, or mid-cycle around 72 hours post-dose. Results return in 2-3 weeks with physician review tied to the selected timing window. This is a monitoring tool, not a broad longevity screen.
A Healthspan physician reviews the sirolimus result in light of the selected timing window, reported dose, frequency, and goals. The interpretation is geared toward rapamycin protocol decisions instead of general health screening.
What to Know
Signature approach
The panel is built around timing. Peak testing shows absorption, trough testing shows clearance before the next dose, and mid-cycle testing shows how quickly the drug is moving through the body between doses. Physician review connects the result to dose, frequency, brand, and goals, which is more useful for weekly longevity dosing than a generic sirolimus value alone.
What sets it apart
- Purpose-built rapamycin monitoring. The test answers absorption and clearance questions for weekly sirolimus users. - Three timing windows. Peak, trough, and mid-cycle options map to different dosing decisions. - Low-cost repeatability. At $25 the panel is sized for follow-up after early doses or medication changes.
Before You Order
- Use case. Best for users already taking rapamycin who need a sirolimus level for dose decisions.
- Single analyte. It measures sirolimus only; use another panel for metabolic, lipid, hormone, CBC, inflammation, or organ-function context.
- Timing matters. Book the draw to match the selected peak, trough, or mid-cycle window.
- Turnaround. Results usually take 2-3 weeks.
- State availability. Unavailable in NY, NJ, and RI.
What's tested
What's included
Biomarker categories
Pharmacokinetics (Drug Level)
1 markerWhat’s not included
Outside the panel: metabolic markers, lipids, hormones, inflammation markers, CBC, organ function, biological-age scoring, and a comprehensive health baseline. It is a rapamycin-monitoring test only.
Reference ranges methodology
There is no single public longevity target range for weekly rapamycin use. Healthspan interprets the value against the selected timing window, dose, frequency, and goal, while transplant trough ranges are designed for a different sustained-immunosuppression use case.
Pricing
Starting at
$25
One sirolimus blood serum draw at the selected timing window, physician-reviewed interpretation, dashboard result, partner-lab collection, and HSA/FSA eligibility.
Panel details
Rapamycin Bioavailability Panel
1 biomarker · In Lab blood draw at 2,000+ partner lab locations
Sirolimus blood serum level at one timing window (peak, trough, or mid-cycle); physician-reviewed personalized report; results dashboard; free shipping
Expected first-year cost
$25/yr - $75/yr
In practiceReal-world pricing notes, add-ons, and coverage limits.
One-time price: $25 for one sirolimus blood-level test and physician-reviewed interpretation. Healthspan recommends testing after the first 2-3 doses and again after dose, brand, or frequency changes, so a first year on a stable protocol may involve 1-3 draws, roughly $25 - $75 HSA/FSA eligible. Confirm at checkout that the purchase is the one-time sirolimus panel if any monthly wording appears in the interface.
How it works
- 1
Pick your timing window
Decide whether the draw should land at peak (3-4 hours after a dose), trough (just before the next dose), or mid-cycle (72 hours post-dose). The window you pick determines what the result tells you — absorption, clearance, or metabolism rate.
- 2
Book your lab draw
Schedule the draw at one of 2,000+ partner locations nationwide. The appointment time has to line up with your dosing schedule and the window you chose, so book around your dose, not the other way around.
- 3
In-lab blood draw
Drop in for a quick serum draw. No fasting required, but avoid strenuous exercise in the 12 hours before.
- 4
Physician-reviewed result
Your sirolimus level returns in 2-3 weeks with a physician interpretation tied to the timing window you selected. Plan to retest after the first 2-3 doses and again after any change in dose, brand, or frequency.
US availability
Availability
Not available in 3 US regions
Available in the other 47 US regions.
Exceptions
New Jersey
State regulations restrict DTC lab testing
New York
State regulations restrict DTC lab testing
Rhode Island
State regulations restrict DTC lab testing
Frequently asked questions
Who should order this?
Users already taking rapamycin who want sirolimus blood-level data for absorption, clearance, or dose-timing decisions.
What do peak, trough, and mid-cycle mean?
Peak is around 3-4 hours after dosing, trough is before the next dose, and mid-cycle is around 72 hours after dosing. Each answers a different dosing question.
Is this a full longevity panel?
No. It measures sirolimus only. Use a broader panel for metabolic, lipid, hormone, CBC, inflammation, or organ-function context.
How often should I test?
Healthspan suggests after the first 2-3 doses and again after changes in dose, brand, or frequency.
Where is it available?
At partner labs in 47 states, excluding New York, New Jersey, and Rhode Island.
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