20/20 BioLabs
AI-powered blood tests for the prevention and early detection of cancers and chronic diseases
At-home blood-test company offering inflammation/diet tracking and protein-biomarker cancer-risk scoring from its own CAP-accredited lab
About
20/20 BioLabs is a Gaithersburg, Maryland testing company behind the OneTest product family. The company was incorporated in 2000, operated for years as 20/20 GeneSystems, and began trading on NASDAQ as AIDX in February 2026. Its consumer lineup has two different jobs: OneTest for Longevity pairs 11 inflammation-linked biomarkers with diet scoring, while OneTest for Cancer uses protein tumor markers and AI scoring for multi-cancer risk assessment. Both are ordered online, collected at home or through a draw option, and processed through the company's own CAP-accredited, CLIA-licensed lab.
Reviews
What to Know
Signature approach
20/20 BioLabs centers the OneTest family on blood biomarkers that can be repeated over time. The cancer product uses Roche protein-marker assays and AI scoring to estimate one-year cancer risk. The longevity product uses inflammation markers, the Dietary Inflammatory Index, the Healthy Eating Index, and IBM watsonx.ai to connect lab values with food-level recommendations. The shared advantage is operational: both products run through the company's own Maryland clinical lab instead of being handed off to a general reference lab.
What sets them apart
- Two focused products under one lab roof. OneTest for Longevity is built around inflammation and diet feedback; OneTest for Cancer is built around protein-biomarker cancer-risk scoring.
- Protein-marker cancer testing. The cancer test uses established tumor-associated proteins on Roche IVD assays, then returns a graded risk score that can be followed over annual retests.
- Diet-to-biomarker longevity report. The longevity test connects 11 blood biomarkers with DII and HEI diet scores, then turns the combined signal into dietary recommendations.
- In-house clinical lab. Samples run through 20/20 BioLabs' CAP-accredited, CLIA-licensed lab in Gaithersburg.
Before You Book
- Choose by question first. Use the longevity test for inflammation-and-diet feedback; use the cancer test for protein-biomarker cancer-risk screening. They are complementary, not interchangeable.
- Plan for add-ons. Cancer-test checkout usually includes collection and authorization costs beyond the headline test price. The longevity launch promotion currently includes those items, but that may change after launch.
- Keep standard screening on schedule. OneTest for Cancer can add another signal, especially for annual trend tracking, but it does not replace colonoscopy, mammography, low-dose CT, Pap testing, or clinician-directed follow-up.
- Check availability before ordering. OneTest Standard is not available in New York; Premium is not available in New York, Hawaii, or Alaska.
Services
Longevity & Inflammation Testing
3 offeringsOneTest for Longevity: 11 inflammation biomarkers + Dietary Inflammatory Index scoring
Personalized dietary recommendations powered by IBM watsonx.ai
Quarterly retesting with trend tracking (subscription option)
Multi-Cancer Early Detection
3 offeringsOneTest for Cancer Standard: 7 protein biomarkers, 20+ cancer types screened
OneTest for Cancer Premium: 12 biomarkers, individual risk for 8 common cancers
AI-powered risk scoring with longitudinal tracking via online portal
Collection & Access
3 offeringsAt-home capillary blood collection (fingerstick kit shipped via FedEx)
Partner clinic blood draw option (My One Medical Source, AnyLabTestNow)
Telemedicine medical authorization service
Pricing
Starting at
$189
OneTest for Longevity one-time test from $189; OneTest for Cancer from $199
Typical annual investment
$189/yr - $888/yr
Membership range estimate before any optional add-ons.
What this range includesMembership tiers, testing cadence, and common add-on examples.
OneTest for Longevity is $189/yr for a single baseline or $468/qtr/year for quarterly subscription testing. OneTest for Cancer runs about $238 - $420 after collection and authorization add-ons. A user combining both products annually would usually land around $427 - $888 depending on retesting cadence and cancer-test tier.
In practiceAdd-ons, payment details, and coverage limits.
The simplest entry point is the $189/qtr OneTest for Longevity baseline. Quarterly longevity testing is $39/mo. OneTest for Cancer starts at $199/mo for Standard or $345 for Premium, then adds $39 for self-collection or $55 for a partner-clinic draw, plus $20 for telemedicine authorization unless your own physician signs the order. Practical cancer-test pricing is about $238 - $420 Both product lines are self-pay; cancer testing is HSA eligible, while HSA/FSA status for the longevity test is not stated.
Insurance: Self Pay · HSA/FSA: Partial
OneTest for Cancer (both Standard and Premium) is HSA eligible. OneTest for Longevity HSA/FSA eligibility is not stated on the product site.
Frequently asked questions
What does 20/20 BioLabs offer consumers?
Two at-home blood-test lines. OneTest for Longevity measures 11 inflammation-linked biomarkers and pairs them with diet scoring. OneTest for Cancer measures protein tumor markers and uses AI scoring to estimate multi-cancer risk. Both are processed in the company's CAP-accredited, CLIA-licensed lab in Gaithersburg, Maryland.
How are the two tests different?
OneTest for Longevity is an inflammation-and-diet feedback test. OneTest for Cancer is a protein-biomarker cancer-risk test. They answer different questions and can be used independently or together.
Do I need a doctor's order?
Yes. You can use your own healthcare provider or the company's third-party telemedicine authorization service. The cancer-test authorization is a $20 add-on; the longevity-test authorization is currently included during launch promotion.
Are these tests FDA-approved?
The individual OneTest for Cancer biomarker assays use FDA-approved Roche in-vitro diagnostic kits. The AI-generated composite cancer-risk score is not FDA-cleared, and OneTest for Longevity is a laboratory-developed test. Both run in a CAP-accredited, CLIA-licensed lab.
Are the tests covered by insurance or HSA?
OneTest for Cancer is HSA eligible. The longevity product's HSA/FSA status is not stated. Neither product lists insurance coverage, so plan around self-pay pricing.
Diagnostics
OneTest for Cancer
$At-home multi-cancer blood test using protein tumor markers and AI scoring for annual risk tracking
20/20 BioLabs
OneTest for Longevity
$At-home inflammation and diet feedback test with 11 blood biomarkers, DII and HEI scoring, and AI-generated food guidance
20/20 BioLabs
Details
Accreditations
2CAP (College of American Pathologists)
The lab processing your samples meets the gold-standard accreditation for clinical laboratories, with regular inspections by pathologist peers.
CLIA (Clinical Laboratory Improvement Amendments)
Federally licensed to perform clinical laboratory testing, required for all labs that process human diagnostic specimens in the US.
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